Endocrine Abstracts

Expression of the mt1 melatonin receptor has been described in both the pars tuberalis (PT) and pars distalis (PD) of the rat pituitary gland. Expression of mt1 mRNA and iodomelatonin (IMEL) binding sites is high in the neonate PD but rapidly declines over the initial weeks of postnatal life. In contrast, both mt1 mRNA and IMEL binding sites are preserved in the PT through to adulthood, leading to a marked tissue-specific expression profile.To identify ...